Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Latex hypersensitivity: an update

C P Hamann1

  • 1Clinical Research Department, SmartPractice, Phoenix, AZ 85008.

Allergy Proceedings : the Official Journal of Regional and State Allergy Societies
|January 1, 1994
PubMed
Summary

Natural rubber latex products can cause allergic reactions due to manufacturing chemicals or natural latex proteins. Manufacturing processes significantly impact latex allergenicity, affecting diagnosis and treatment of latex allergies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Natural rubber latex.

Journal of the American Dental Association (1939)·1999
Same author

Natural rubber latex hypersensitivity: incidence and prevalence of type I allergy in the dental professional.

Journal of the American Dental Association (1939)·1998
Same author

Allergies associated with medical gloves. Manufacturing issues.

Dermatologic clinics·1994
Same author

Permeability of latex and thermoplastic elastomer gloves to the bacteriophage phi X174.

American journal of infection control·1993
Same author

Update: immediate and delayed hypersensitivity to natural rubber latex.

Cutis·1993
Same author

Taking up the gauntlet: accepting the challenge of glove evaluation.

Journal of healthcare materiel management·1993

Area of Science:

  • Immunology
  • Materials Science
  • Occupational Health

Background:

  • Natural rubber latex (NRL) products are known to elicit hypersensitivity reactions.
  • These reactions can manifest as immediate or delayed types.
  • Both chemical additives and inherent latex proteins contribute to NRL allergenicity.

Purpose of the Study:

  • To explore the mechanisms of delayed and immediate hypersensitivity to NRL.
  • To investigate how manufacturing processes influence NRL allergenicity.
  • To discuss the implications for diagnosing and treating NRL allergies.

Main Methods:

  • Review of existing literature on NRL hypersensitivity.
  • Analysis of chemical components and protein antigens in NRL.
  • Examination of manufacturing variables affecting NRL allergenicity.

Main Results:

  • Delayed hypersensitivity is primarily linked to chemical additives like antidegradants and accelerators.
  • Immediate hypersensitivity is attributed to naturally occurring protein antigens in NRL.
  • Manufacturing stages critically affect the concentration of these protein antigens, thus altering the final product's allergenicity.

Conclusions:

  • Understanding the role of manufacturing is crucial for managing NRL allergies.
  • Regulatory considerations are important for product safety and patient care.
  • Further research into manufacturing-allergenicity relationships can improve diagnostic and therapeutic strategies.

Related Experiment Videos