Related Experiment Videos
Living donor for liver transplantation
C E Broelsch1, M Burdelski, X Rogiers
1Department of Surgery, University Hospital Eppendorf, University of Hamburg, Germany.
Hepatology (Baltimore, Md.)
|July 1, 1994
Summary
Living related liver transplantation offers a viable solution for end-stage liver disease, with European centers reporting an 85% survival rate. This technique provides excellent quality grafts, enabling timely, elective procedures.
Area of Science:
- Hepatology
- Transplantation Surgery
- Organ Donation
Background:
- Living related liver transplantation (LRTR) has been performed globally since 1989, primarily in the US and Japan.
- This study introduces the first series of LRTR in Europe, addressing organ shortages.
Purpose of the Study:
- To report the outcomes of the first series of living related liver transplantation in Europe.
- To discuss technical improvements and procurement details for successful LRTR.
- To highlight the advantages of LRTR in managing end-stage liver disease, especially in pediatric cases.
Main Methods:
- Twenty living related liver transplantation surgeries were performed over 13 months.
- Detailed description of living donor liver procurement procedures.
- Analysis of patient survival rates and technical complications.
Main Results:
- Overall patient survival rate of 85% was achieved.
- Elective transplantations (n=13) had a 100% survival rate.
- Technical complications included arterial thrombosis (1) and bile leaks (5), with subsequent improvements discussed. No intraoperative complications or need for heterologous blood transfusion.
Conclusions:
- Living related liver transplantation is an effective treatment for end-stage liver disease, particularly in children.
- It offers a readily available, high-quality graft for optimal, elective transplantation.
- LRTR can overcome cadaveric organ shortages and is crucial for regions with underdeveloped organ procurement systems.