Related Experiment Videos
TaqI dimorphic site in a human pancreatic phospholipase A2 (PLA2) gene localized on chromosome 12
P M Frossard1, P E Newman, G G Lestringant
1Department of Pathology, Faculty of Medicine and Health Sciences, Al Ain, United Arab Emirates.
Human Genetics
|June 1, 1994
Abstract:
We report the identification of a TaqI dimorphic site in the first intron of a human phospholipase A2 gene that has been localized on chromosome 12. This single two-allele polymorphism was detected by DNA blot hybridization using a full-length, 584 bp human phospholipase A2 cDNA isolated from a human lung lambda gt10 cDNA library. Fragment lengths were detected at either 1.3 kb or 2.2 kb. The PIC value of this dimorphism was 0.369 in a random population of 353 Caucasians.