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Microphthalmos with cyst: a clinical study

P K Agrawal1, H Kumar

  • 1Department of Ophthalmology, King George's Medical College, Lucknow.

Indian Journal of Ophthalmology
|December 1, 1993
PubMed
Summary
This summary is machine-generated.

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Microphthalmos with cyst, a condition arising from abnormal embryonic development, presents varied symptoms. Surgical removal and orbital conformers are crucial for maintaining facial symmetry in pediatric patients.

Area of Science:

  • Ophthalmology
  • Developmental Biology
  • Pediatric Surgery

Background:

  • Embryonic fissure closure defects and optic vesicle invagination anomalies can lead to microphthalmos with cyst.
  • This condition presents a spectrum of clinical manifestations and ocular abnormalities.

Observation:

  • Three pediatric patients presented with unilateral microphthalmos with cyst.
  • Clinical signs included lower eyelid swelling or a draining sinus with a small or absent eyeball.
  • Ocular examination revealed posterior segment abnormalities like retinal disorganization and colobomas.

Findings:

  • Microscopic analysis showed cysts connected to colobomas, composed of fibrovascular tissue and neuroectodermal layers.
  • Treatment involved cyst excision or combined microphthalmic eye and cyst removal.

Related Experiment Videos

  • Post-operative orbital conformer use was essential for symmetrical orbital development.

    • Implications:

    • Early diagnosis and surgical intervention are vital for managing microphthalmos with cyst.
    • The use of orbital conformers is critical for achieving satisfactory cosmetic and functional outcomes in pediatric cases.
    • Understanding the developmental origins aids in predicting and managing associated ocular malformations.