[Chemotaxis and spontaneous migration of neutrophil leukocytes from patients with diabetes]

The spontaneous migration and chemotaxis of leukocytes has been measured in 103 diabetic patients with 1 ans 2 type diabetes controlled and uncontrolled diabetes as well as in patients those treated with oral hypoglycemic drugs or insulin. The obtained results have been compared with appropriate parameters from 32 healthy individuals. Our findings indicate increase of spontaneous migration of PMN. The disturbances in PMN functions are not related to diabetes type. Treatment with oral diabetic drugs resulted an decrease in spontaneous migration values.