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[Cardiac complications of halofantrine: continuous electrocardiographic study (holter) in 20 patients]
E Monlun1, P Le Metayer, M C Receveur
1Clinique médicale propédeutique, médecine interne et maladies tropicales, hôpital Saint André, CHU Bordeaux, France.
La Revue De Medecine Interne
|January 1, 1993
Abstract:
Three cases of long QT-interval due to halofantrine were documented in 1992 in France. Two of them had a congenital long QT-interval (Romano-Ward syndrome). We performed a prospective study of cardiac monitoring in 20 patients taking halofantrine. Minimal ECG changes were noted with lengthening of the QT-interval. Systematic ECG is necessary before giving halofantrine.