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[A new threat: Xanthomonas maltophilia infection. Apropos of 50 cases]
P Rispal1, J Maugein, C Lasseur
1Clinique de médecine interne et maladies infectieuses, hôpital Haut-Lévêque, Pessac.
Abstract:
In an attempt to further characterize infections due to Xanthomonas maltophilia (XM), we reviewed 50 case reports observed in our institution. XM is emerging as an important nosocomial pathogen in immunocompromised patients, especially those receiving broad spectrum antimicrobial antibiotherapy. Distinction between colonisation and infection is often difficult. XM presents a therapeutic challenge because of its tendency to exhibit multiple resistance.
Insights
Xanthomonas maltophilia (XM) infections are a growing concern in immunocompromised patients, often linked to broad-spectrum antibiotics. This pathogen presents significant therapeutic challenges due to its multiple drug resistance.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Medicine
Context:
- Xanthomonas maltophilia (XM) is an emerging nosocomial pathogen.
- Infections are frequently observed in immunocompromised patients.
- Broad-spectrum antimicrobial therapy is a common predisposing factor.
Purpose:
- To further characterize infections caused by Xanthomonas maltophilia (XM).
- To review institutional case reports of XM infections.
Summary:
- A review of 50 case reports identified Xanthomonas maltophilia (XM) as a significant nosocomial pathogen.
- Distinguishing between colonization and infection by XM can be challenging.
- XM infections pose therapeutic difficulties due to multidrug resistance.
Impact:
- Highlights the increasing clinical importance of Xanthomonas maltophilia (XM).
- Underscores the challenges in managing XM infections in vulnerable patient populations.
- Emphasizes the need for effective antimicrobial strategies against resistant strains.