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Updated: Aug 19, 2026

07:43
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Corticotropic macroadenoma: clinical, hormonal, radiological and immunocytochemical study of 6 cases]
R Maréchaud1, C Humbert, F Bonneau
1Service de médecine interne, endocrinologie, hôpital Jean Bernard, Poitiers.
Abstract:
We report 6 cases of corticotroph macroadenomas which show heterogeneity of clinical and biological features (from Cushing's syndrome to silent adenoma) and heterogeneity of immunocytochemical staining. One patient reported on had skin hyperpigmentation and ACTH hypersecretion without clear abnormal adrenocortical function; we believe that this patient's plasma contained ACTH with very low bioactivity.
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