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Ureteric necrosis after kidney transplantation
Acta Chirurgica Scandinavica. Supplementum
|January 1, 1976
Summary
Ureteral necrosis occurred in 3.4% of kidney transplants using uretero-cystostomy. Long cold ischemia may increase this risk, though more research is needed for definitive conclusions.
Area of Science:
- Nephrology
- Urology
- Transplant Surgery
Background:
- Uretero-cystostomy is a common reconstructive procedure in kidney transplantation.
- Graft ureter complications can impact transplant success.
Purpose of the Study:
- To investigate the incidence and potential risk factors of ureteral necrosis following uretero-cystostomy in cadaver kidney transplantation.
Main Methods:
- Retrospective analysis of 298 cadaver kidney transplantations using uretero-cystostomy.
- Evaluation of graft ureter complications, specifically necrosis.
- Analysis of potential contributing factors including malformations, donor nephrectomy issues, histocompatibility, rejection crises, and ischemia duration.
Main Results:
- Ureteral necrosis occurred in 10 cases (3.4%).
- Identified causes in 3 cases included ureteral malformations and donor nephrectomy injury.
- No correlation found between ureteral necrosis and histocompatibility, rejection crises, or warm ischemia duration.
- A trend towards higher incidence with prolonged cold ischemia was observed, but requires further investigation.
Conclusions:
- Ureteral necrosis is a rare but significant complication after uretero-cystostomy in kidney transplantation.
- Prolonged cold ischemia time may be a risk factor for ureteral necrosis.
- Further studies are warranted to confirm the impact of cold ischemia on ureteral healing and necrosis.