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[Effects of extracts from Phyllanthus urinaria L. on HBsAg production in PLC/PRF/5 cell line]
Abstract:
Experiment on the effect of extracts from Phyllanthus urinaria on HBsAg production in PLC/PRF/5 human hepatoma cell line showed that the production was decreased markedly 48 hours after the treatment of cells with 2-4 mg/ml Phyllanthus urinaria, especially in combination with 10(-5) mol/L of Ara-A. The decrease of extracellular HB-sAg excretion seems to stem from the inhibition of intracellular HBsAg formation.