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Preparation and properties of buserelin suspensions
F Ryszka1, B Dolińska, B Szulc
1Department of Applied Pharmacy and Drug Technology Medical Silesian Academy, Sosnowiec, Poland.
Bollettino Chimico Farmaceutico
|March 1, 1994
Abstract:
Obtaining and some properties of suspensions with buserelin-there were obtained buserelin suspensions with zinc ions with pH 7.2-7.5 and hormone: zinc molar ratio from 1:2.5 to 1:500. The obtained buserelin suspensions show moderated hormone release in vitro and prolonged action in vivo. The pulsating buserelin release from suspensions has been found in vitro and in vivo.