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Splenic sepsis in sickle cell disease
J D Cavenagh1, A E Joseph, S Dilly
1Division of Haematology, St George's Hospital Medical School, London.
British Journal of Haematology
|January 1, 1994
Summary
Sickle cell disease (SCD) patients are at high risk for spleen infections, including abscesses and infarcts. Prompt diagnosis is crucial for individuals with SCD presenting with fever and abdominal pain.
Area of Science:
- Medicine
- Hematology
- Infectious Diseases
Background:
- Sickle cell disease (SCD) is characterized by functional hyposplenism and impaired phagocyte function.
- These factors increase susceptibility to infections, particularly in the spleen.