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Treponema denticola as a model for polar adhesion and cytopathogenicity of spirochetes
R P Ellen1, J R Dawson, P F Yang
1Dept of Periodontics, Faculty of Dentistry, University of Toronto, Canada.
Trends in Microbiology
|April 1, 1994
Abstract:
Recent studies suggest that the tip-oriented adhesion of Treponema denticola is a consequence of polar clustering of its adhesins on contact with the substratum and is compatible with viability. Such adhesion to cells stimulates a host of cytoskeletal and volume regulatory changes. These studies may give insight into mechanisms of colonization and cytopathogenicity of other pathogenic spirochetes.