Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Technical and scientific developments in exposure marker methodology

E J Sampson1, L L Needham, J L Pirkle

  • 1Centers for Disease Control and Prevention (CDC), Public Health Service, Atlanta, GA 30341.

Clinical Chemistry
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discharge Opioids are Unnecessary Following Radical Cystectomy.

Urology·2022
Same author

Importance of enhanced mass resolution in removing interferences when measuring volatile organic compounds in human blood by using purge-and-trap gas chromatography/mass spectrometry.

Journal of the American Society for Mass Spectrometry·2013
Same author

Hypertension and chronic kidney disease: controversies in pathogenesis and treatment.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2013
Same author

Chromosomal microarray impacts clinical management.

Clinical genetics·2013
Same author

Safe handling of chemical toxicants and control of interferences in human tissue analysis for dioxins and furans.

Environmental science & technology·2011
Same author

Adaptive optics and the eye (super resolution OCT).

Eye (London, England)·2011
Same journal

Comparison of Information-Dependent Acquisition and Sequential Window Acquisition of All Theoretical Mass Spectra for Untargeted Drug Testing on a Linear Ion Trap-Pulsing Quadrupole-Time of Flight Mass Spectrometer.

Clinical chemistry·2026
Same journal

Patterns of One-Year Change in HbA1c and Continuous Glucose Monitoring (CGM) Metrics in Older Adults with Type 2 Diabetes.

Clinical chemistry·2026
Same journal

TSH Pediatric Reference Intervals: Lack of CALIPER Applicability to US-Based Populations.

Clinical chemistry·2026
Same journal

Rapid Detection of Hemoglobinopathy Variants Using One-Step Library Preparation and Nanopore Sequencing.

Clinical chemistry·2026
Same journal

Editor's Note: Circulating Proteolytic Products of Carboxypeptidase N for Early Detection of Breast Cancer.

Clinical chemistry·2026
Same journal

In Reply to Reflexing NT-proBNP for sFlt-1/PlGF Ratios That Fall into the Measurement Uncertainty for Preeclampsia Risk Classification.

Clinical chemistry·2026
See all related articles

New methods for measuring human exposure to environmental toxicants improve accuracy. This review highlights advances in exposure marker methodology for better risk assessment and policy decisions.

Area of Science:

  • Environmental Health Sciences
  • Toxicology
  • Epidemiology

Background:

  • Measuring human exposure to environmental toxicants is crucial for public health.
  • Advances in analytical techniques are transforming exposure assessment.
  • Reliable exposure data informs environmental policy and scientific interpretation.

Purpose of the Study:

  • To review major technical and scientific developments in exposure marker methodology.
  • To discuss the characteristics and quality of laboratory methods for internal dose estimation.
  • To provide recommendations for improving human toxicant exposure data.

Main Methods:

  • Review of laboratory methods for measuring biomarkers of exposure.
  • Comparison of direct biomarker methods with indirect exposure assessment tools (e.g., questionnaires).

Related Experiment Videos

  • Consideration of human pharmacokinetic data, sampling, and quality assurance.

    • Main Results:

    • Significant progress in laboratory technology and analytical standards enhances exposure marker reliability.
    • Biomarker data provides a more direct measure of internal dose compared to indirect methods.
    • Challenges remain in sampling, quality assurance, and data interpretation.

    Conclusions:

    • Improved exposure marker methodology increases the reliability of environmental health risk assessments.
    • Further research and data collection are needed to enhance our understanding of human toxicant exposures.
    • These advancements aid environmental scientists, epidemiologists, and policymakers in characterizing exposure.