Related Experiment Video
Updated: Aug 10, 2026

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
Published on: January 4, 2011
Central corneal light scatter in long-term diabetics
R Holden1, G A Shun-Shin, N A Brown
1Clinical Cataract Research Unit, Nuffield Laboratory of Ophthalmology, Oxford, UK.
Abstract:
Changes in corneal thickness have been correlated with severity of diabetic retinopathy. Measuring light scatter at the central cornea may reflect the changes in corneal thickness and hence the retinopathy. This study compared the peak central corneal light scatter between 22 insulin-dependent diabetic patients with disease of at least 10 years' duration and 29 controls. No significant difference was found in the light-scattering properties of the central cornea between the two groups. This technique does not offer an alternative method of screening for diabetic retinopathy.
Related Concept Videos
Photoreceptors and Visual Pathways
Diabetic Retinopathy
Diabetic Nephropathy

