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Plateletpheresis during plasma collection

M Rubertelli1, F Marafioti, C Mazzon

  • 1Haematology and Blood Bank, S. Chiara Hospital, Trento, Italy.

The International Journal of Artificial Organs
|December 1, 1993
PubMed
Summary
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New plasma collection systems efficiently prepare platelet concentrate (PC) and platelet-poor plasma (PPP). Autopheresis-C yielded higher platelet counts than Haemonetics PCS, demonstrating plasma-plateletpheresis

Area of Science:

  • Transfusion Medicine
  • Hematology

Background:

  • New systems for collecting platelet concentrate (PC) and platelet-poor plasma (PPP) are available.
  • Current methods require evaluation for efficiency and product quality.

Purpose of the Study:

  • To assess the routine preparation of PC from plasma donors.
  • To evaluate the time efficiency and yield of PC and PPP.
  • To compare two apheresis systems: Haemonetics PCS and Autopheresis-C.

Main Methods:

  • A 3-year study (1990-1992) involving 3503 apheresis procedures.
  • Utilized 2 Haemonetics PCS machines and 3 Autopheresis-C machines.
  • Collected PC and PPP from normal plasma donors.

Main Results:

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  • Successfully met all regional hospital demands for PC.
  • Platelet yield: 1.95 x 10^11 (PCS) vs. 3.2 x 10^11 (Auto-C).
  • Collection times were similar: 56 min (PCS) vs. 63 min (Auto-C).

    • Conclusions:

    • Plasma-plateletpheresis is an efficient and competitive collection system.
    • Autopheresis-C demonstrated superior platelet yield compared to Haemonetics PCS.
    • The systems effectively provide PC and source plasma for transfusion needs.