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Related Experiment Videos

Therapeutic plasma adsorption. A review

G Avanzi1, F Cepparrone, R Lombardo

  • 1Blood Transfusion Centre, University Hospital of Firenze, Italy.

The International Journal of Artificial Organs
|December 1, 1993
PubMed
Summary

Alternative blood filtration techniques are gaining traction for treating autoimmune diseases, offering new options beyond traditional plasma exchange. Emerging methods like cascade filtration and novel absorption columns show promise for improved patient outcomes.

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Area of Science:

  • Medical Science
  • Immunology
  • Biotechnology

Background:

  • Traditional plasma exchange is a common treatment for autoimmune diseases.
  • Emerging alternative techniques offer new therapeutic possibilities.
  • Filtration separates blood cells from plasma for further treatment.

Purpose of the Study:

  • To review alternative techniques to traditional plasma exchange.
  • To highlight advancements in filtration and absorption therapies.
  • To discuss the growing use of these alternative methods in clinical practice.

Main Methods:

  • Review of emerging filtration and absorption techniques.
  • Discussion of new column systems and products (e.g., dextran sulphate, tryptophane, anti-human lipoprotein antibodies).

Related Experiment Videos

  • Focus on Protein A and therapeutic plasmapheresis variations.

    • Main Results:

    • Cascade filtration and column absorption are increasingly utilized.
    • New self-regenerating column systems and specialized products are available.
    • Protein A shows significant potential, with different versions yielding varied results but good clinical outcomes.

    Conclusions:

    • Alternative filtration and absorption techniques are expanding treatment options for autoimmune diseases.
    • Advancements in column technology and materials are enhancing therapeutic efficacy.
    • Protein A-based plasmapheresis demonstrates promising clinical results despite variations.