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Birth order, interpregnancy interval and birth outcomes among Filipino infants
1Office of Population Research, Princeton University.
Insights
First births face the most risks. High birth order and short interpregnancy intervals combined increase risks, but this high-risk group is small, limiting overall impact on birth outcomes.
Area of Science:
- Maternal and Child Health
- Perinatal Epidemiology
- Demography
Background:
- Birth order and interpregnancy interval are known factors influencing infant health.
- Previous research indicates potential risks associated with specific birth circumstances.
Purpose of the Study:
- To investigate the combined effects of birth order and interpregnancy interval on various birth outcomes.
- To identify specific high-risk groups for adverse birth outcomes.
Main Methods:
- Analysis of data from a longitudinal study of 2063 births in the Philippines.
- Statistical modeling to assess the impact of birth order and interpregnancy interval on birthweight, gestational age, and other infant metrics.
- Control for confounding factors including maternal age, education, smoking, health history, and nutritional status.
Main Results:
- First births were found to be the most disadvantaged across all birth order and spacing categories.
- Combined risks of short interpregnancy intervals (< 6 months) and high birth order (≥ 5th) were significant.
- These combined risks were specific to infants with both attributes; no excess risk was observed for lower-order births with short intervals or high-order births with long intervals.
- The observed patterns held true for all five birth outcomes and neonatal mortality, even after controlling for covariates.
Conclusions:
- The combination of high birth order and short interpregnancy interval poses the greatest risk to infant health outcomes.
- Interventions targeting this specific high-risk group (fewer than 2% of births) may have a limited impact (1-2%) on reducing overall low birthweight and neonatal mortality.
- Understanding these nuanced relationships is crucial for optimizing maternal and child health strategies.
Abstract:
This study examines the effects of birth order and interpregnancy interval on birthweight, gestational age, weight-for-gestational age, infant length, and weight-for-length in a sample of 2063 births from a longitudinal study in the Philippines. First births are the most disadvantaged of any birth order/spacing group. The risks associated with short intervals (< 6 months) and high birth order (fifth or higher) are confined to infants who have both attributes; there is no excess risk associated with short previous intervals among lower-order infants, nor for high birth order infants conceived after longer intervals. This pattern is observed for all five birth outcomes and neonatal mortality, and persists in models that control for mother's age, education, smoking, family health history and nutritional status. Since fewer than 2% of births are both short interval and high birth order, the potential reduction in the incidence of low birthweight or neonatal mortality from avoiding this category of high-risk births is quite small (1-2%).
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