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Hepatic injury caused by benzbromarone
M M van der Klauw1, P M Houtman, B H Stricker
1Department of Internal Medicine II, University Hospital Dijkzigt, Rotterdam, The Netherlands.
Journal of Hepatology
|March 1, 1994
Summary
Benzbromarone, a gout medication, was linked to liver injury in a case study. Drug reintroduction confirmed benzbromarone as the cause of hepatocellular injury, highlighting the need for careful monitoring.
Area of Science:
- Hepatology
- Clinical Pharmacology
- Toxicology
Background:
- Drug-induced liver injury (DILI) is a significant clinical concern.
- Benzbromarone is a uricosuric agent used for gout management.
- Methyldopa is an antihypertensive medication with a known potential for liver toxicity.