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Updated: Jul 25, 2026
23:06
The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Multidrug-resistant tuberculosis in the New York State prison system, 1990-1991
S E Valway1, R B Greifinger, M Papania
1Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, GA 30333.
The Journal of Infectious Diseases
|July 1, 1994
Summary
Multidrug-resistant tuberculosis (MDR-TB) outbreaks in New York State prisons were widespread. High rates and mortality, particularly among HIV-infected inmates, highlight urgent needs for improved infection control and transfer policies.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- Multidrug-resistant tuberculosis (MDR-TB) poses a significant public health threat, especially within congregate settings like correctional facilities.
- Previous outbreaks suggested MDR-TB was prevalent in New York State (NYS) prisons.
Purpose of the Study:
- To investigate the epidemiology and scope of MDR-TB outbreaks in NYS prisons during 1990-1991.
- To assess the characteristics and outcomes of inmates diagnosed with MDR-TB.
Main Methods:
- Linking inmate lists with TB registries (1990-1992).
- Reviewing medical records and inmate movement histories.
- Analyzing drug susceptibility patterns and human immunodeficiency virus (HIV) coinfection rates.
Main Results:
- 171 inmates diagnosed with TB (rate 156.2/100,000), significantly higher than national and previous NYS inmate rates.
- 37% of cultured TB cases were MDR-TB.
- 97% of MDR-TB cases were coinfected with HIV, and 87% died.
Conclusions:
- MDR-TB was widespread and associated with high mortality in NYS prisons.
- Infection control and inmate transfer policies require urgent reevaluation to prevent TB transmission in correctional settings.
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