[Effects of TSH on thyroid ribonucleic acids (author's transl)]
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Updated: Oct 8, 2026

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses
Published on: February 25, 2011
Abstract:
Bovine thyroid slices were incubated with TSH (20 mU/ml) in the presence of 0.04 microgram/ml actinomycin D. The incorporation of 3H Adenosine or 3H Uridine in the microsomal RNA fraction was studied. TSH enhanced the labeling of this RNA. After gel electrophoresis in 100% formamide, the distribution of the radioactivity showed a relatively larger incorporation of the precursors in the region corresponding to heavy molecular weight RNA (3 X 10(6) daltons). These data suggest that TSH could exert a specific effect on transcription in the thyroid gland.
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