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[Lymphedema and hypothyroidism]

N P Iurkevich, T V Savchenko

    Klinicheskaia Meditsina
    |January 1, 1994
    PubMed
    Summary
    This summary is machine-generated.

    Lymphedema patients, particularly those with primary disease, frequently exhibit hypothyroidism-like thyroid dysfunction. Early thyroid screening and hormone therapy are recommended for effective lymphedema management.

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    Area of Science:

    • Endocrinology
    • Vascular Medicine
    • Genetics

    Background:

    • Lymphedema is a chronic condition characterized by fluid accumulation and tissue swelling.
    • Primary lymphedema has a genetic origin, while secondary lymphedema results from damage to the lymphatic system.
    • Thyroid dysfunction is a common endocrine disorder with various potential health impacts.

    Observation:

    • The study involved 1191 lymphedema patients, comprising 635 with primary and 536 with secondary lymphedema.
    • Thyroid dysfunction, resembling hypothyroidism, was identified in a significant majority (80%) of primary lymphedema cases.
    • Thyroid hormone level measurements corroborated the observed thyroid dysfunction.

    Findings:

    • A high prevalence of hypothyroidism-like thyroid dysfunction exists in patients with primary lymphedema.

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  • Thyroid hormone levels are significantly altered in lymphedema patients, correlating with the disease.
  • The thyreoidin test is a valuable diagnostic tool for assessing thyroid function in lymphedema patients.

    • Implications:

    • Routine thyroid function testing is advisable for all lymphedema patients, especially those with primary lymphedema.
    • Integrated treatment strategies incorporating thyroid hormone replacement therapy may improve lymphedema outcomes.
    • Further research into the pathophysiological links between lymphedema and thyroid dysfunction is warranted.