[HPV genital infections + CIN. The immunological patterns, loop electroablation and beta-interferon]

Sixteen patients with genital HPV associated with CIN were treated with electroablation using a diathermic loop and immunomodulation with human beta interferon. Changes in immunological, cyto-histological and clinical parameters were observed pre- and post-treatment. Thirteen cases showed an excellent response. Disease was persistent in three cases. The authors report an improvement, even if statistically non-significant, in some immune parameters and confirm the value of associating physical therapy with immunomodulating treatment.