Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Current diagnosis in pathology]

J Briner1

  • 1Institut für Klinische Pathologie, Universität Zürich.

Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis
|June 7, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mutational analysis of the tumor-suppressor gene wt1 - detection of a novel homozygous point mutation in sporadic unilateral wilms-tumor.

International journal of oncology·2011
Same author

Homozygosity for a nonsense mutation in the alpha-tropomyosin slow gene TPM3 in a patient with severe infantile nemaline myopathy.

Neuromuscular disorders : NMD·2000
Same author

Human eukaryotic initiation factor EIF2C1 gene: cDNA sequence, genomic organization, localization to chromosomal bands 1p34-p35, and expression.

Genomics·1999
Same author

Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors.

Cancer research·1999
Same author

Enteric infections and diarrhea in human immunodeficiency virus-infected persons: prospective community-based cohort study. Swiss HIV Cohort Study.

Archives of internal medicine·1999
Same author

[Progressive multifocal leukoencephalopathy: morphologic possibilities of diagnostic classification methods and in situ hybridization].

Ceskoslovenska patologie·1999
Same journal

[In Process Citation]

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1999
Same journal

[A case from practice (306). Erythema (chronicum) migrans (stage I of Lyme borreliosis].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
Same journal

[A case from practice (305). Recurrent erysipelas--tinea pedis et unginum--chronic venous insufficiency].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
Same journal

[Neuroendocrine tumors of the stomach (stomach carcinoid)].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
Same journal

[Time of drug intake in hypertension and angina pectoris. A controlled monitoring study].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
Same journal

[Mental suffering IN patients with parkinsonism].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
See all related articles

Modern pathology techniques like electron microscopy and molecular methods enhance diagnostic accuracy. These advancements improve the identification of diseases, from viral infections to cancers, aiding in precise diagnosis and research.

Area of Science:

  • Pathology
  • Biotechnology
  • Molecular Biology

Context:

  • Classical light microscopy has been significantly enhanced by modern pathological techniques.
  • Electron microscopy, immunofluorescence, histochemistry, and immunohistochemistry have revolutionized ultrastructural and functional assessments.
  • Formalin-fixed, paraffin-embedded tissues are now amenable to precise diagnostic analysis using antibodies.

Purpose:

  • To highlight the advancements in pathology driven by modern research methods.
  • To demonstrate the application of various techniques in improving diagnostic capabilities.
  • To showcase the utility of molecular biology in disease detection and research.

Summary:

  • Modern pathology integrates techniques such as electron microscopy, immunohistochemistry, and molecular methods for enhanced diagnostics.

Related Experiment Videos

  • Molecular techniques like in situ hybridization and polymerase chain reaction enable precise detection of viral nucleic acids and bacterial pathogens.
  • These methods are crucial for cancer research, exemplified by IGF2 detection in nephroblastomas, and tumor diagnosis, such as T-cell receptor rearrangement in lymphomas.

    • Impact:

    • Improved resolution and functional assessment in pathology.
    • Precise diagnosis of poorly differentiated tumors and identification of difficult-to-cultivate microorganisms.
    • Significant progress in cancer research and the molecular diagnosis of lymphomas and other cancers.