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Endobronchial HIV associated lymphoma

T C Keys1, M A Judson, C E Reed

  • 1Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston 29425.

Thorax
|May 1, 1994
PubMed
Summary

A 27-year-old man with HIV experienced sudden hemoptysis. Diagnosis of large cell immunoblastic lymphoma was confirmed via bronchoscopy of a carinal mass.

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Area of Science:

  • Pulmonology
  • Oncology
  • Infectious Diseases

Background:

  • Human Immunodeficiency Virus (HIV) infection can predispose individuals to various opportunistic infections and malignancies.
  • Malignancies in HIV-infected individuals can present with atypical symptoms and require thorough diagnostic evaluation.

Observation:

  • A 27-year-old male with a known history of HIV presented with acute onset hemoptysis.
  • Initial flexible bronchoscopy identified a significant carinal mass causing partial obstruction of both main bronchi.

Findings:

  • Histopathological examination via rigid bronchoscopy confirmed the carinal mass to be large cell immunoblastic lymphoma.
  • This rare lymphoma subtype can occur in immunocompromised individuals.

Implications:

  • Early and accurate diagnosis of pulmonary masses in HIV patients is crucial for timely treatment initiation.
  • Carinal masses, though uncommon, should be considered in the differential diagnosis of hemoptysis in HIV-positive patients.
  • Further research into the management and outcomes of such rare presentations is warranted.

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