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[A trial of using a dry bifidobacterin preparation with newborn risk groups to prevent acute intestinal infections]
Insights
Administering bifidumbacterin to newborns positively influenced intestinal microflora formation. This probiotic preparation reduced acute enteric infections by three times in infants during their first three months.
Area of Science:
- Microbiology
- Pediatrics
- Gastroenterology
Background:
- Infant gut microbiome development is crucial for health.
- Early life infections pose significant risks to newborns.
- Probiotics are explored for modulating infant gut microbiota.
Purpose of the Study:
- To evaluate the effect of bifidumbacterin on infant intestinal microflora.
- To assess the prophylactic efficacy of bifidumbacterin against infections in newborns.
Main Methods:
- A randomized controlled trial involving newborn infants.
- Administration of dried bifidumbacterin preparation to the test group.
- Bacteriological analysis of intestinal microflora and infection surveillance.
Main Results:
- Bifidumbacterin positively impacted the formation of intestinal microflora.
- Infants receiving bifidumbacterin had 3x fewer acute enteric infections in the first 3 months.
- A notable prophylactic effect was observed against skin and buccal mucosa infections.
Conclusions:
- Bifidumbacterin is effective in promoting healthy infant gut microbiota.
- This probiotic demonstrates significant protective effects against common infant infections.
- Bifidumbacterin shows promise as a prophylactic agent for newborns.
Abstract:
The dried preparation of bifidumbacterin was administered to newborn infant during 4-6 days of their stay in a maternity clinic. The test group consisted of 110 infants and the control group, of 115 infants. Bacteriological studies indicated that the administration of bifidumbacterin produced a positive effect on the formation of the intestinal microflora in infants. During the first 3 months of life the registered cases of acute enteric infections among the children of the test group were 3 times less frequent than among the children of the control group. A perceptible prophylactic effect produced by this preparation with respect to purulent septic infections of the skin and the buccal mucosa was also noted.