Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

T-cell deficiency in Suffolk lambs

Z Zomborszky1, E Horn, S Tuboly

  • 1Faculty of Animal Science, PANNON University of Agriculture, Kaposvár, Hungary.

Acta Veterinaria Hungarica
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Suicidal ideation in patients with skin conditions: A multicentre European study.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

A cross-sectional study on gender differences in body dysmorphic concerns in patients with skin conditions in relation to sociodemographic, clinical and psychological variables.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Bullying and skin diseases.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Dermatological patients with itch report more stress, stigmatization experience, anxiety and depression compared to patients without itch: Results from a European multi-centre study.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Psychotrauma and the skin.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020
Same author

'The psychosocial burden of alopecia areata and androgenetica': a cross-sectional multicentre study among dermatological out-patients in 13 European countries.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019

Suffolk lambs exhibit lower T-cell percentages and anemia compared to Booroola sheep, impacting their disease resistance. Treatments with levamisole and vitamin B12 improved these parameters in Suffolk lambs.

Area of Science:

  • Veterinary Immunology
  • Animal Science
  • Sheep Health

Background:

  • Suffolk sheep flocks frequently experience respiratory diseases, unlike healthy Booroola sheep under similar conditions.
  • Immune and blood parameters differ between sheep breeds, influencing disease susceptibility.

Purpose of the Study:

  • To compare immunological and haematological parameters between Suffolk and Booroola sheep of various age groups.
  • To investigate potential causes for the lower disease resistance observed in Suffolk lambs.

Main Methods:

  • Analysis of T and B cell percentages and blastogenesis capacity in response to mitogens (Concanavalin A and Phaseolus vulgaris lectin).
  • Measurement of red blood cell count, packed cell volume, and hemoglobin concentration.
  • Assessment of treatment effects with levamisole (immunomodulator) and vitamin B12.

Related Experiment Videos

Main Results:

  • Suffolk lambs showed significantly lower T-cell percentages and Concanavalin A-induced blastogenesis at 6 months.
  • Suffolk lambs exhibited significantly lower red blood cell counts and packed cell volumes, indicating anemia.
  • Treatment with levamisole and vitamin B12 successfully corrected T-cell deficiency and anemia in Suffolk lambs.

Conclusions:

  • T-cell deficiency and anemia may contribute to the reduced resistance of Suffolk lambs to opportunistic pathogens.
  • Further research is needed to determine the genetic and environmental contributions to these differences.