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Intervention in hypercholesterolemic college students: a pilot study

M P McGowan1, A Joffe, A K Duggan

  • 1Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.

The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine
|March 1, 1994
PubMed
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A 7-week health education intervention improved nutritional knowledge in hypercholesterolemic college students. It also protected students with very high LDL-C from significant increases in cholesterol levels long-term.

Area of Science:

  • Cardiovascular Health
  • Nutritional Science
  • Preventive Medicine

Background:

  • Atherosclerosis originates in childhood, with cholesterol levels often persisting into adulthood.
  • Early intervention for elevated cholesterol is crucial for long-term cardiovascular health.
  • Hypercholesterolemia in college students presents a critical window for intervention.

Purpose of the Study:

  • To evaluate the effectiveness of a health education intervention on hypercholesterolemic college students.
  • To assess the impact of nutrition and behavior modification on lipid profiles and knowledge.
  • To determine if early intervention can mitigate long-term increases in low-density lipoprotein cholesterol (LDL-C).

Main Methods:

  • Thirty-nine university students with LDL-C levels at or above the 75th percentile were randomized.

Related Experiment Videos

  • The intervention group (n=20) received 7 weekly sessions on nutrition and behavior modification.
  • The control group (n=19) received a lecture and video on diet and cholesterol.
  • Knowledge, attitudes, and lipid profiles (LDL-C) were assessed at baseline, 8 weeks, and 8 months.

    • Main Results:

    • The intervention group demonstrated significantly superior nutritional knowledge post-intervention (p < 0.001).
    • At 8 months, the intervention group experienced a smaller increase in LDL-C compared to the control group (0.05 mmol/L vs. 0.34 mmol/L, p = 0.045).
    • Students with baseline LDL-C at or above the 95th percentile showed the most benefit from the intervention.

    Conclusions:

    • A 7-week health education intervention significantly enhances nutritional knowledge in college students.
    • This intervention effectively protects hyperlipidemic students, particularly those with very high LDL-C, from significant long-term LDL-C increases.
    • Targeted interventions in young adults are vital for managing hypercholesterolemia and preventing cardiovascular disease.