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Updated: Aug 12, 2026

Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA
Published on: November 14, 2017
[Effect of alpha-tocopherol and ubiquinone on mitochondrial RNA polymerase activity. The role of tocopherol-binding
Abstract:
It has been shown that alpha-tocopherol within the complex with tocopherol-binding proteins, in contrast with free tocopherol, decreases the RNA-polymerase activity in isolated rat liver mitochondria. Both free and complexed to proteins alpha-tocopherol increases the RNA-polymerase activity in isolated nuclei. The effect of alpha-tocopherol is conditioned mostly by the nature of the tocopherol-binding proteins. It has been established that ubiquinone complexed to tocopherol-binding proteins from mitochondria can also change the level of RNA synthesis. The effect of alpha-tocopherol and ubiquinone are not additive.
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