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Evaluation of restricted diffusion in cylinders. Phosphocreatine in rabbit leg muscle
P van Gelderen1, D DesPres, P C van Zijl
1Faculty of Applied Physics, University of Technology Delft, The Netherlands.
Journal of Magnetic Resonance. Series B
|March 1, 1994
Abstract:
Interpretation of NMR diffusion data is complicated in the presence of diffusion barriers. In this study, restricted diffusion in cylinders is evaluated. A method is presented to determine the diameter of the cylinder and the unrestricted diffusion coefficient from the dependence of the trace of the diffusion tensor with diffusion time. This method is valid even if the orientation of the cylinders is unknown and varies within the sample. An example is given for the diffusion of phosphocreatine in the cylindrically shaped fibers of rabbit skeletal muscle.