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Updated: Aug 3, 2026
Viability Assays for Cells in Culture
Published on: January 20, 2014
Differences in sensitivity to farnesol toxicity between neoplastically- and non-neoplastically-derived cells in
I Adany1, E M Yazlovitskaya, J S Haug
1Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City 66103.
Abstract:
Six neoplastically-derived cell lines and three cell lines derived from normal tissues were compared for their sensitivity to isoprenoid trans-trans farnesol. Assays of cell numbers and of protein concentrations per culture revealed greater sensitivity of neoplastic cells than of the normal cells. Similar differences were obtained from the comparison of incorporation of [methyl-3H]choline into cellular lipids, with neoplastic cells showing greater inhibition than normal cells.
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