Systemic treatment of recurrent candidal vulvovaginitis by Itraconazole

20 women suffering from recurrent candidal vulvovaginitis were treated with Itraconazole, with a single oral dose of 200 mg/day administered after the main meal for three days. The diagnosis was obtained by microscope and culture tests, and check were made 7 and 30 days after completion of the treatment. The symptom score, assessed on the individual patients by means of the classic clinical parameters, showed a significant drop both at the first and second level checks. In our study, the culture tested negative in 75% of cases at the first check, and in 85% of cases at the second check. All patients completed the study without claiming any major side effects.