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The metabolism of ethosuximide
J S Millership1, J Mifsud, P S Collier
1School of Pharmacy, Queen's University of Belfast, UK.
European Journal of Drug Metabolism and Pharmacokinetics
|October 1, 1993
Abstract:
The metabolism of the antiepileptic drug ethosuximide (3-ethyl-3-methylpyrollidine-2,5-dione) (I) in animals and humans is reviewed. Chiral aspects of the metabolism of ethosuximide are discussed. Clarification of the precise nature of the hydroxymetabolites of ethosuximide is presented.