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Association between Meckel's diverticulum and Crohn's disease: a retrospective review

H J Andreyev1, R A Owen, I Thompson

  • 1St Mark's Hospital, London.

Gut
|June 1, 1994
PubMed

Insights

Patients with Crohn's disease have a significantly higher prevalence of Meckel's diverticulum, occurring 2-3 times more frequently than in the general population. The reason for this increased occurrence of Meckel's diverticulum in Crohn's disease patients remains unclear.

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Crohn's disease is a chronic inflammatory bowel condition.
  • Meckel's diverticulum is a congenital abnormality of the small intestine.

Purpose of the Study:

  • To investigate the prevalence of Meckel's diverticulum in patients undergoing right hemicolectomy for Crohn's disease.
  • To compare this prevalence to expected rates in the general population.

Main Methods:

  • Retrospective review of operation notes and pathology records.
  • Analysis of data from 294 consecutive patients with Crohn's disease.

Main Results:

  • Meckel's diverticulum was identified in 17 patients (5.8%).
  • This represents a 2-3 fold increase compared to the general population prevalence.
  • No heterotopic mucosa was found in the examined Meckel's diverticula from this cohort.

Conclusions:

  • The study confirms a higher incidence of Meckel's diverticulum in Crohn's disease patients.
  • The underlying cause for this association requires further investigation.
  • The clinical significance of this finding warrants discussion.

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