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Biological activity of some coumarins from Sri Lankan Rutaceae
A A Gunatilaka1, D G Kingston, E M Wijeratne
1Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg 24061-0212.
Journal of Natural Products
|April 1, 1994
Abstract:
Twelve coumarins isolated from plants of the Rutaceae collected in Sri Lanka have been subjected to a mechanism-based anticancer bioassay employing DNA repair-deficient and repair-proficient yeasts. Of these, seselin [10] and xanthyletin [11] were found to be active. Seselin also exhibited moderate cytotoxicity.