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Mesothelioma in the atrioventricular node. Case report

H Kawano1, R Okada, Y Kawano

  • 1Research Laboratory for Cardiovascular Pathology, Juntendo University School of Medicine, Tokyo, Japan.

Japanese Heart Journal
|March 1, 1994
PubMed
Summary

A rare cardiac tumor, an atrioventricular node mesothelioma, was discovered during autopsy in a patient with complete atrioventricular block. Histochemical analysis suggested an endodermal origin for this controversial tumor type.

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Area of Science:

  • Cardiovascular Pathology
  • Oncology
  • Histopathology

Background:

  • Complete atrioventricular block necessitates pacemaker implantation.
  • Cardiac tumors, particularly at the atrioventricular node, are rare.
  • The histogenesis of atrioventricular node mesothelioma remains debated.

Observation:

  • Autopsy revealed a cardiac tumor in the atrioventricular node region of a 64-year-old patient.
  • The patient had a history of complete atrioventricular block and a permanent pacemaker.
  • The patient's cause of death was colon cancer.

Findings:

  • The cardiac tumor was identified as a mesothelioma of the atrioventricular node.
  • Histochemical analysis provided evidence suggesting an endodermal origin.

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  • This finding contributes to the understanding of mesothelioma histogenesis.

    • Implications:

    • Further research into the endodermal origin of atrioventricular node mesothelioma is warranted.
    • Understanding tumor origin can inform diagnostic and therapeutic strategies.
    • This case highlights the importance of comprehensive autopsy in rare cardiac conditions.