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A case of pulmonary amyloidosis associated with multiple myeloma successfully treated with dimethyl sulfoxide
T Iwasaki1, T Hamano, K Aizawa
1Second Department of Internal Medicine, Hyogo College of Medicine, Japan.
Acta Haematologica
|January 1, 1994
Abstract:
A 57-year-old man with IgG multiple myeloma developed pulmonary infiltration caused by pulmonary amyloidosis, for which continuous transdermal dimethyl sulfoxide (DMSO) treatment was given. After 8 weeks from the start of DMSO treatment, a dramatic reduction of pulmonary infiltration as determined by chest roentgenogram was observed, and arterial blood gas levels were improved. No serious side effect of DMSO was encountered. We conclude that a therapeutic trial with transdermal DMSO administration brought about a marked regression of the pulmonary infiltrate.