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The effect of midazolam on median nerve somatosensory evoked potentials
1Department of Anesthesiology, Medical College of Wisconsin, Milwaukee 53226.
Journal of Clinical Monitoring
|May 1, 1994
Abstract
Objective:
To quantify the effect of an induction dose of midazolam on median nerve somatosensory evoked potentials.
Methods:
We studied 10 patients undergoing lumbar spine surgery. After an induction dose of intravenous midazolam was given, MNEPs were collected for ten minutes. After ten minutes the patients were intubated and their anesthetic was supplemented with 0.5% isoflurane, narcotic, and N2O.
Results:
We found a clinically significant decrease in amplitude and an insignificant delay in latency.
Conclusion:
When midazolam is used as an anesthetic induction agent, a decrease in amplitude can be expected.