Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Evaluation of renal function by factor analysis using 99mTc-MAG3]

C Hosokawa1, Y Ushijima, T Okamura

  • 1Department of Radiology, Osaka City University.

Kaku Igaku. the Japanese Journal of Nuclear Medicine
|May 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Atezolizumab plus bevacizumab versus lenvatinib or sorafenib in non-viral unresectable hepatocellular carcinoma: an international propensity score matching analysis.

ESMO open·2022
Same author

Nonalcoholic steatohepatitis in hepatocarcinoma: new insights about its prognostic role in patients treated with lenvatinib.

ESMO open·2021
Same author

Lactulose ingestion causes an increase in the abundance of gut-resident bifidobacteria in Japanese women: a randomised, double-blind, placebo-controlled crossover trial.

Beneficial microbes·2021
Same author

Possible de novo clear cell carcinoma in the contralateral ovary 9 years after fertility-sparing surgery for Stage IA clear cell ovarian carcinoma.

International cancer conference journal·2019
Same author

Prebiotic effect of two grams of lactulose in healthy Japanese women: a randomised, double-blind, placebo-controlled crossover trial.

Beneficial microbes·2019
Same author

Auraptene in the Peels of Citrus Kawachiensis (Kawachibankan) Contributes to the Preservation of Cognitive Function: A Randomized, Placebo-Controlled, Double-Blind Study in Healthy Volunteers.

The journal of prevention of Alzheimer's disease·2018

Factor analysis objectively evaluates renal function using 99mTc-mercapto-acetyltriglycine (MAG3) renal scintigraphy. This method aids in assessing chronic kidney disorders by analyzing MAG3 kinetics without region of interest selection.

Area of Science:

  • Nuclear Medicine
  • Radiopharmacology
  • Medical Imaging

Background:

  • Chronic kidney disease assessment requires accurate renal function evaluation.
  • 99mTc-mercapto-acetyltriglycine (MAG3) is a radiotracer used for renal scintigraphy.
  • Traditional methods for renal function assessment can be subjective.

Purpose of the Study:

  • To evaluate the application of factor analysis for assessing renal function using 99mTc-MAG3.
  • To investigate the ability of factor analysis to differentiate renal parenchymal and pelvic components.

Main Methods:

  • Factor analysis was applied to serial renal scintigrams obtained over 30 minutes post-injection of 99mTc-MAG3.
  • Data from 10 patients with chronic renal disorders were analyzed.
  • Two-factor and three-factor analyses were performed based on serum creatinine levels.

Related Experiment Videos

Main Results:

  • Factor analysis successfully separated renal parenchymal and pelvic components in 8 out of 10 patients with lower creatinine levels (Cre ≤ 2.9 mg/dl).
  • In patients with higher creatinine levels (Cre ≥ 3.0 mg/dl), a three-factor analysis was required for separation.
  • The separated factors correlated with segmental renograms, indicating functional differentiation.

Conclusions:

  • Factor analysis provides an objective method for evaluating renal function using 99mTc-MAG3 scintigraphy.
  • This technique allows for the assessment of renal function without the need for manual region of interest (ROI) selection.
  • Factor analysis demonstrates potential for improved diagnostic accuracy in chronic renal disorders.