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Updated: Aug 16, 2026

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Published on: May 26, 2010
[Transesophageal atrial stimulation--a test for myocardial ischemia]
A Jović1, M Nekić-Borcilo, R Troskot
1Odjel za kardiologiju Opće bolnice u Zadru.
Insights
Transesophageal atrial pacing (TAP) is a reliable method for diagnosing myocardial ischemia in coronary artery disease (CAD) patients. This technique shows comparable sensitivity to stress testing, offering a valuable alternative for cardiac assessment.
Area of Science:
- Cardiology
- Diagnostic Imaging
- Medical Technology
Context:
- Coronary artery disease (CAD) diagnosis often relies on stress testing.
- Myocardial ischemia assessment requires accurate and feasible diagnostic tools.
- Transesophageal atrial pacing (TAP) offers a potential alternative for ischemia detection.
Purpose:
- To evaluate the clinical utility and feasibility of transesophageal atrial pacing (TAP) for diagnosing myocardial ischemia.
- To compare the diagnostic performance of TAP with standard bicycle-stress testing in CAD patients.
- To determine if TAP can reliably induce ischemic ECG changes similar to those seen during exercise.
Summary:
- Forty patients with CAD underwent transesophageal atrial pacing (TAP).
- Ischemic ECG changes, similar to bicycle-stress testing, were induced in 35 patients (87.5%).
- TAP demonstrated comparable sensitivity to stress testing in detecting myocardial ischemia, with good feasibility.
Impact:
- Transesophageal atrial pacing (TAP) is a reliable alternative for assessing coronary artery disease (CAD).
- TAP can be integrated with other noninvasive methods for routine cardiac patient diagnostics.
- This study supports TAP as a valuable tool in the noninvasive diagnostic armamentarium for myocardial ischemia.
Abstract:
The aim of the present study was to determine clinical value and the feasibility of transesophageal atrial pacing (TAP) in diagnosing myocardial ischemia in patients with coronary artery disease (CAD). Forty patients with CAD and with significant ST-segment depression in a standard 12-lead ECG during bicycle-stress testing underwent TAP. Rapid atrial stimulation was performed by using a very flexible six-polar polyurethane pacing lead introduced through the nares into the esophagus and connected to the stimulator allowing selection of rate, output voltage and pulse duration. The satisfactory atrial pacing was obtained by 28 +/- 6 V output and 7 +/- 1 ms pulse duration. Of 40 patients who underwent TAP, ischemic ECG changes were induced in 35 (u = 2,24 p < 0,05) and were very similar to those that occurred during bicycle-stress testing according to their intensity and distribution and affected ECG leads with comparable peak rate-pressure products. This suggests comparable sensitivity of TAP and bicycle-stress testing in discovering myocardial ischemia in CAD patients. Four patients had negative test for myocardial ischemia and in one TAP was discontinued because of intolerable chest discomfort. In conclusion, TAP is a reliable alternative technique for the assessment of coronary artery disease. In combination with some other noninvasive methods (echocardiography, scintigraphy, i.v. digital angiography), it has become a routine diagnostic procedure in cardiac patients.
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