Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Malalignment and degenerative arthropathy

K Tetsworth1, D Paley

  • 1Division of Orthopaedic Surgery, University of Maryland School of Medicine, Baltimore.

The Orthopedic Clinics of North America
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reverse dynamisation: a modern perspective on Stephan Perren's strain theory.

European cells & materials·2021
Same author

Congenital pseudarthrosis of the tibia: biological and biomechanical considerations to achieve union and prevent refracture.

Journal of children's orthopaedics·2019
Same author

The Osseointegration Group of Australia Accelerated Protocol (OGAAP-1) for two-stage osseointegrated reconstruction of amputated limbs.

The bone & joint journal·2016
Same author

Tibial lengthening over intramedullary nails: A matched case comparison with Ilizarov tibial lengthening.

Bone & joint research·2016
Same author

Life- and limb-threatening infections following the use of an external fixator.

The bone & joint journal·2015
Same author

Irreducible lateral dislocation of patella with rotation.

Journal of surgical case reports·2014
Same journal

New Technologies.

The Orthopedic clinics of North America·2026
Same journal

Recent Innovations and Applications of Custom 3D Printed Cages for Critical Bone Defects in Foot and Ankle Surgery.

The Orthopedic clinics of North America·2026
Same journal

Application of New Technologies: Patient-specific Instrumentation and Artificial Intelligence in the Field of Foot and Ankle.

The Orthopedic clinics of North America·2026
Same journal

Robotic-Assisted Latissimus Dorsi Transfers Around the Shoulder.

The Orthopedic clinics of North America·2026
Same journal

Blood Flow Restriction Therapy for the Upper Extremity: An Emerging Adjunct for Patient Recovery and Rehabilitation.

The Orthopedic clinics of North America·2026
Same journal

The Emerging Roles for 3 Dimensional Printing in Orthopedics: Applications, Evidence, and Future Directions.

The Orthopedic clinics of North America·2026
See all related articles

Lower extremity joint malalignment can lead to knee stress and degenerative joint disease. While direct evidence is limited, orthopedic literature strongly supports malalignment as a cause of arthropathy.

Area of Science:

  • Orthopedics
  • Biomechanics

Background:

  • Joint alignment and orientation are critical for lower extremity function.
  • Malalignment can negatively impact articular cartilage and joint mechanics.
  • Understanding the relationship between malalignment and joint degeneration is crucial for clinical practice.

Purpose of the Study:

  • To review the evidence supporting the hypothesis that joint malalignment contributes to degenerative arthropathy.
  • To discuss the role of static and dynamic malalignment in joint health.
  • To highlight findings from animal and cadaver models regarding malalignment effects.

Main Methods:

  • Review of existing orthopedic literature, including retrospective studies and cadaveric models.
  • Analysis of laboratory animal models simulating malalignment.

Related Experiment Videos

  • Examination of biomechanical principles related to force transmission in malaligned joints.

    • Main Results:

    • Malalignment disturbs normal force transmission across the knee.
    • Altered stress distribution in malaligned joints has been demonstrated.
    • Retrospective studies suggest malalignment progresses to degenerative arthropathy over time.

    Conclusions:

    • Substantial evidence supports the hypothesis that lower extremity malalignment causes degenerative arthropathy.
    • Dynamic considerations of gait may be more clinically relevant than static alignment.
    • Further prospective studies are needed to definitively establish causality.