[Lupus nephritis with nephrotic syndrome successfully treated with plasmapheresis and cyclophosphamide]

In a 45 years woman with advanced nephrotic syndrome in the course of SLE IgM nephropathy, transient renal failure made the continuation of the conventional steroid therapy impossible. Applied as a saving life therapy, plasmapheresis followed by i.v. pulses of cyclophosphamide, caused resolution of lupus nephritis. Since the withdrawal of cyclophosphamide, the patient has been observed for 18 month, showing no evidence of recurrence of lupus nephritis.