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Hepatic helical CT: contrast material injection protocol

W D Foley1, R G Hoffmann, F A Quiroz

  • 1Department of Radiology, Medical College of Wisconsin, Milwaukee 53226.

Radiology
|August 1, 1994
PubMed
Summary
This summary is machine-generated.

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Monophasic and biphasic contrast material injection protocols for hepatic helical computed tomography (CT) yield similar results. Both methods are effective when adapted for rapid-sequence helical acquisitions, offering comparable hepatic enhancement.

Area of Science:

  • Radiology
  • Medical Imaging

Background:

  • Helical computed tomography (CT) is a key imaging modality for hepatic evaluation.
  • Optimizing contrast material injection protocols is crucial for diagnostic accuracy in hepatic CT.

Purpose of the Study:

  • To develop and compare contrast material injection protocols for hepatic helical CT.
  • To assess the efficacy of monophasic versus biphasic protocols in enhancing liver visualization.

Main Methods:

  • Monophasic and biphasic helical CT protocols were evaluated using contrast material with a 50 g iodine load.
  • Different injection rates and durations were employed: 3 mL/sec for 60s (monophasic) or 5 mL/sec for 10s + 2 mL/sec for 65s (biphasic).
  • Aortic and hepatic enhancement curves were constructed in 109 patients (58 men, 51 women) aged 22-77 years.

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Main Results:

  • Monophasic protocol achieved higher peak aortic enhancement (180 HU ± 47) compared to biphasic (150 HU ± 24).
  • Peak hepatic enhancement was comparable between both protocols (63-64 HU ± 15).
  • Calculated equilibrium times were 95.1s for monophasic and 101.4s for biphasic, with no significant difference in contrast enhancement index (P < .4).

Conclusions:

  • Both monophasic and biphasic contrast material injection protocols are effective for hepatic helical CT.
  • Protocol optimization for the rapid temporal window of helical acquisition ensures equivalent diagnostic results.
  • These findings support the use of tailored injection strategies for enhanced hepatic imaging.