[Changes in the indices of apparatus coagulography in patients with viral hepatitis]

210 patients with acute viral hepatitis B (AVH) were examined by apparatus coagulography with regard to severity of the disease. Considerably prolonged start and end of coagulation, increased minimal and maximal amplitudes were established in the early period of the infection. The disorders correlated with severity of AVH. New parameter--clot retraction index (CRI)--was suggested for objective estimation of disease severity and early diagnosis of acute hepatic encephalopathy (AHE). The index provides characteristics of dynamic state of blood clot at the moment of its maximal extraction. CR1 is recommended for early diagnosis or preclinical AHE in patients with AVH.