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Lectin effects on HIV-1 infectivity
L Hammar1, I Hirsch, A Machado
1Department of Veterinary Virology, Biomedical Center, Uppsala, Sweden.
Annals of the New York Academy of Sciences
|June 6, 1994
Abstract:
Lectins with specificity for terminal mannose residues and anti-mannan antibodies are assumed to neutralize HIV-1 by binding to the viral glycoproteins. In this report we demonstrate that one such agents, the lectin from Galanthus nivalis (GNA), blocks infection also at the target cell level.