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[Liver transplantation in pediatrics. Nutritional measures]
I Recuenco1, M Ruano, R Gutiérrez
1Servicio de Farmacia, Hospital La Paz, Madrid, España.
Nutricion Hospitalaria
|March 1, 1994
Summary
Malnutrition is common in liver transplant candidates. Immediate post-transplant nutrition support, specifically total parenteral nutrition (TPN), may reduce infection risk and ICU stay in pediatric liver transplant recipients.
Area of Science:
- Pediatric Intensive Care
- Transplant Surgery
- Nutritional Support
Background:
- Malnutrition is prevalent in liver transplant candidates.
- Pre-operative nutritional interventions are challenging.
- Post-transplant nutritional support is crucial for pediatric liver transplant recipients.
Purpose of the Study:
- To evaluate the impact of immediate post-transplant total parenteral nutrition (TPN) on pediatric liver transplant outcomes.
- To compare infection rates, intensive care unit (ICU) length of stay, and survival rates between children receiving TPN and those receiving enteral nutrition.
Main Methods:
- Retrospective study of pediatric liver transplant recipients from 1992.
- Two groups: Group A (immediate TPN) and Group B (enteral nutrition).
- Analysis of clinical records, focusing on nutritional interventions, complications, ICU stay, and survival.
Main Results:
- Group A (TPN) showed a 3.2 relative risk of infection compared to Group B.
- Group A patients had a significantly longer ICU stay (13.4 days) than Group B (6.28 days).
- Survival rates were 86.6% for TPN group and 71.4% for enteral nutrition group (not significant).
Conclusions:
- Immediate post-transplant TPN in pediatric liver transplant recipients was associated with increased infection risk and longer ICU stays.
- While survival rates were high in the TPN group, the study could not definitively link TPN to improved outcomes due to variability in patient conditions.