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Dog as an animal model for neurostimulation
M Hassouna1, J S Li, M Elhilali
1Urology Research Laboratory, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada.
Neurourology and Urodynamics
|January 1, 1994
Summary
Dogs are valuable models for studying neural stimulation effects on the nervous system, particularly for bladder evacuation. This review examines canine neurostimulation research, covering methods, rationale, and anatomical considerations.
Area of Science:
- Neuroscience
- Urology
- Animal Models
Background:
- The dog is a significant animal model for studying the central and peripheral nervous systems.
- Numerous studies have utilized dogs for neurostimulation and neuromodulation research focused on bladder evacuation.
Purpose of the Study:
- To review prominent English literature on neurostimulation using dogs as an experimental model.
- To examine various neurostimulation modes, their rationale, and limitations in canine models.
- To review anatomical features of neural bladder control and technical aspects of canine bladder neurostimulation.
Main Methods:
- Literature review of English scientific publications.
- Analysis of studies employing dogs for neurostimulation and neuromodulation of the bladder.
- Examination of anatomical and technical aspects relevant to canine bladder neurostimulation.
Main Results:
- Dogs serve as a crucial model for understanding neural control of bladder function.
- Various neurostimulation techniques have been explored in canine models.
- The review synthesizes information on the efficacy, rationale, and drawbacks of different methods.
Conclusions:
- The canine model offers valuable insights into neurostimulation for bladder evacuation.
- Understanding canine neuroanatomy and stimulation techniques is essential for research.
- Further research can build upon existing canine neurostimulation studies for therapeutic advancements.