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Related Experiment Videos

Nervous function after right hemispherectomy

A R Damásio, A Lima, H Damásio

    Neurology
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    This study shows a 20-year-old woman experienced significant brain adaptation after a hemispherectomy for severe head trauma. Her cognitive and motor functions showed remarkable recovery, indicating positive neuroplasticity in the mature brain.

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    Area of Science:

    • Neuroscience
    • Neurosurgery
    • Neuroplasticity

    Background:

    • A 20-year-old female presented with intractable seizures and behavioral changes following severe head trauma at age five.
    • Previous psychomotor development was normal prior to the traumatic brain injury.

    Purpose of the Study:

    • To evaluate the functional outcomes and adaptive capacity of the mature brain following hemispherectomy.
    • To assess neurological deficits and higher nervous function post-surgery.

    Main Methods:

    • Hemispherectomy was performed to address medically refractory epilepsy and behavioral disturbances.
    • Post-operative neurological and functional assessments were conducted.

    Main Results:

    • The patient exhibited minimal impairment in higher nervous functions associated with the removed hemisphere.

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  • Significant improvement in left-sided motor performance and minimal sensory deficits were observed.
  • No hemianopia was present; an enlarged right visual field and left ear preference in dichotic listening were noted.
  • Conclusions:

    • The findings suggest substantial positive adaptation and neuroplasticity can occur in the mature brain.
    • Hemispherectomy can lead to favorable outcomes in selected cases of severe traumatic brain injury with epilepsy.