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[The effect of T cells in pathogenesis of glomerular nephritis]
Zhonghua Bing Li Xue Za Zhi = Chinese Journal of Pathology
|December 1, 1993
Abstract:
T lymphocytes were infused to congenital athymic nude mice to reconstitute its cellular immunological function. Success was then achieved in inducing crescentic glomerular nephritis in the nude mice. No pathological changes were observed in the control group of nude mice which did not receive T lymphocyte infusion. Results of this study suggest that T lymphocytes play an important role in the pathogenesis of crescentic glomerular nephritis.