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Corneal decompensation in mitochondrial ophthalmoplegia plus (Kearns-Sayre) syndrome. A clinicopathologic case report
T S Chang1, D R Johns, W J Stark
1Eye Pathology Laboratory, Wilmer Ophthalmologic Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Cornea
|May 1, 1994
Abstract:
The authors describe the clinical, molecular genetic, and pathologic findings of a patient with corneal decompensation associated with the mitochondrial ophthalmoplegia plus (Kearns-Sayre) syndrome. Ultrastructurally abnormal mitochondria were observed and possibly implicate this organelle in the pathogenesis of corneal edema.